Bioanalytical / Analytical Chemistry

Lovelace Biomedical has extensive expertise in bioanalytical chemistry, with specialized laboratories and experienced bioanalytical method development/validation and sample analysis chemists. Whether working with a small molecule, or qPCR bioanalysis Lovelace has experience developing new assays or transferring existing methods. These methods can support pharmacokinetic, toxicokinetic, biodistribution, and in vivo metabolism studies. The analyses can be conducted to evaluate parent molecules or metabolites in a full range of matrices, including blood, plasma, serum, urine, CSF, pleural fluid and tissue. Whether your study is an exploratory research study or a GLP toxicology study Lovelace has the Bioanalytical team to support your needs.

Small Molecule




Our Analytical/Bioanalytical Chemistry Department provides a state-of-the-art infrastructure with experience in quantitative analysis to support dose formulation, aerosol characterization, pharmacokinetic, toxicokinetic, and biomarker sample analysis. Methods can be transferred or developed de novo. Methods can be validated to meet regulatory compliance or utilized in non-regulatory drug development. Analytes can include small molecules, proteins, mAb, cytokines, biomarkers, or peptides. Capabilities include:

  • Quantitative analysis
  • Development/transfer of bioanalytical assays
  • Validation of methods
  • GLP compliance
  • LC-MS, ELISA, MSD, PCR, Flow Cytometry platforms
  • Multiple analytes
  • Endogenous analytes
  • Immunology, Cell-based Assays
  • Flow Cytometry
Bioanalytical Fact Sheet


  • Mass Spectrometer Systems
    • Sciex API 5000’s, 5500’s and 6500’s
  • Gas Chromatography
    • Agilent 7890’s, MS, TCD & ECD detectors, liquid and head autosampler
  • Liquid Chromatography
    • Agilent 1100/1200, MS; DAD, VWD, RID, FLD detectors
    • Waters Acquity UPLC equipped with PDA; FLD, ECD detectors
    • Plate Readers Systems
    • Molecular Diagnostics i3x Plate Reader’s
  • PCR Systems
    • BioRad CFX 96 and 384 well systems
  • Biomarker systems
    • MSD/Luminex
    • Tecan/Eppendorf/TomTec liquid handers