Preclinical research also known as preclinical study or preclinical development is the phase of research conducted prior to clinical trials. It is a type of non-clinical study where drug-related data are carefully sourced and compiled in order to gain deep understanding of its feasibility of use on humans and product safety profile.

Preclinical research mainly discovers the ideal dosage levels that are safe for use on first human trials. Some of the product types commonly subjected to preclinical research are drugs, medical devices, or other diagnostic tools and therapy solutions. In general, only 1 in 5,000 compounds get drug approval after undergoing the strenuous process of preclinical research.